Darolutamide Manufacturer Supply Chemical/Pharmaceutical API CAS 1297538-32-9 ODM-201 Darolutamide

Basic Info

Model NO.	Darolutamide R-127
Common Name	ODM-201
CAS Number	1297538-32-9
Molecular Weight	398.846
Density	1.4±0.1 g/cm3
Boiling Point	719.5±60.0 °c at 760 Mmhg
Molecular Formula	C19h19cln6o2
Flash Point	388.9±32.9 °c
Transport Package	Bag, Drum
Origin	China

Product Description

of Darolutamide:
Product Name: Darolutamide CAS NO:1297538-32-9

Synonyms:
ODM-201;
N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide;

Chemical & Physical Properties of Darolutamide:
Appearance: Light Yellow Liquid
Assay : ≥99.0%
Density:1.4 g/cm3
Boiling Point:719.5ºC at 760 mmHg
Flash Point:388.9ºC


ODM-201, also known as Darolutamide, is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509, inhibits testosterone-induced nuclear translocation of AR. Importantly, ODM-201 also blocks the activity of the tested mutant ARs arising in response to antiandrogen therapies, including the F876L mutation that confers resistance to enzalutamide and ARN-509. In addition, ODM-201 reduces the growth of AR-overexpressing VCaP prostate cancer cells both in vitro and in a castration-resistant VCaP xenograft model. ODM-201 overcomes resistance to AR-targeted therapies by antagonizing both overexpressed and mutated ARs. ODM-201 is currently in a phase 3 trial in CRPC.

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
Quality Assurance COA will be provided before making payment.Product standards strictly complies to COA.If any quality problem verified , 100% replace product or return payment.If still feel worried, sample can be provided. FAQQ1. What's the MOQ?
A: It is based on the different product. Some are 1g and some are 1 ton. Plesae be free to consult our salesman.Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FeDex will be 10 days to you.Q3. If I need less than the MOQ, is it possible.A: Yes. If less than MOQ. the price will be 5% more than the MOQ. It based on the different product. Plesae be free to consult our salesman.Q4. Can you supply the free sample?
A: Usually it is possible. It based on the different product. Plesae be free to consult our salesman.Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers.The shelf life will be 2 years.Q6: What's your main payment method?
A: T/T, west union, money gram, order online.Our services1) One to one business communication.2) Any inquiries will be replied within 12 hours.3) We offer convenient one-station purchasing service.Our professionaland thoughtful after-sales service eliminates your worries.4) We has 10 years' exporting experience in active pharmaceutical ingredient products.,Strictly on selecting raw materials.5) OEM/ODM Available.6) Reasonable & competitive price, fast lead time.7) Sample is available for your evaluation & Formulation development.8) Faster delivery: Sample order in stock and 3-5 workdays for bulk production.9) Excellent after-sale service.
Packaging & Delivery

Packing :	1kg/bag ,25kg/bag;25kg/drum; according to your requirements
Port:	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time :	3-5 working days upon received the payment
For mass orders, it will be delivered by air or sea.Depending on your location, please allow 1-5 business days for your order to arrive.For small order, please expect 3-7 days by UPS DHL EMS.For mass order, please allow 5-8 days by Air, 15-30 days by Sea.